New findings on the pharmacokinetics of cannabidiol - CBD and older horses
Contents:
In a recently published study titled "Pharmacokinetics of cannabidiol in a randomized crossover study in older horses," Turner et al. (2022) investigated the metabolism and distribution of CBD in older horses. The study was published in the Journal of Veterinary Research and provides valuable insights into the use of CBD and horses.
aim of the study
The main aim of the study was to analyze the pharmacokinetic properties of cannabidiol in older horses, investigating how CBD is absorbed, distributed, metabolized and excreted in the horses' bodies. In particular, the researchers wanted to find out how CBD behaves in different body tissues in order to better assess its potential therapeutic applications.
study structure
The researchers conducted a randomized crossover study using older horses as subjects. This type of study design means that each horse received both CBD and a placebo at different times to ensure direct comparability of the results. The horses were given a defined dose of CBD, and the researchers tracked CBD concentrations in the blood and other body fluids over a set period of time.
results of the study
The key findings of the study include:
Fast absorption and distribution:
After administration, CBD was absorbed relatively quickly by the horses' bodies and distributed in the bloodstream. The researchers were able to detect significant CBD concentrations in the blood shortly after ingestion.
Half-life and metabolism:
The study found that CBD has an intermediate half-life in older horses, meaning that it is not immediately eliminated from the body but remains in the system for several hours. This suggests that regular dosing of CBD may be useful to maintain a constant concentration in the body.
Safety and tolerability:
No serious side effects were observed, indicating that CBD is well tolerated even in older horses. This is especially important because older animals are often more sensitive to new treatments.
significance of the study
The study by Turner et al. (2022) provides important insights into the pharmacokinetics of CBD in older horses and opens up new possibilities for therapeutic use. Since older horses often suffer from chronic conditions such as arthritis or pain, CBD could be a promising natural supplement to relieve symptoms.
Research shows that CBD is not only quickly absorbed but also well tolerated, further strengthening its potential use in the veterinary field. However, more studies are needed to determine the long-term effects and optimal dosage for different age groups and health conditions.
Conclusion
The study shows that CBD is a safe and well-absorbed substance in older horses. The knowledge gained could help veterinarians better understand how CBD can be used as a complementary therapy for older horses to reduce chronic pain, inflammation, and other age-related conditions. However, further research will be needed to fully understand and optimize the use of CBD in horses.
Source and study:
Turner, S. et al. (2022). Pharmacokinetics of cannabidiol in a randomized crossover study in older horses. Journal of Veterinary Research. 18;83(9):ajvr.22.02.0028. Doi: 10.2460/ajvr.22.02.0028. Downloaded 26 March 2024, from [source]
For legal reasons, we would like to point out that the effects of hemp and cannabinoids (CBD) described here refer exclusively to public scientific reports and specialist reports, publications and user experiences and are not to be understood as instructions for use or promises of healing. The text is in no way a substitute for professional advice from a doctor and may not be used as a basis for independent diagnosis and the start, change or termination of treatment of illnesses. Always consult your trusted doctor if you have any health questions or complaints!
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